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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS7
All Species:
22.73
Human Site:
S356
Identified Species:
38.46
UniProt:
P49802
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49802
NP_002915.3
495
57668
S356
K
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Chimpanzee
Pan troglodytes
XP_001159739
487
56751
S356
K
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Rhesus Macaque
Macaca mulatta
XP_001095075
499
57951
S360
K
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Dog
Lupus familis
XP_537503
683
78241
S346
R
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Cat
Felis silvestris
Mouse
Mus musculus
O54829
469
54704
P341
M
D
E
A
L
K
D
P
V
G
R
E
Q
F
L
Rat
Rattus norvegicus
P49803
477
55673
G343
E
A
L
K
D
P
V
G
R
E
Q
F
L
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514330
608
70692
S356
K
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Chicken
Gallus gallus
XP_419551
506
58927
S356
K
F
L
E
S
E
F
S
S
E
N
L
R
F
W
Frog
Xenopus laevis
NP_001079945
471
54554
P343
L
N
E
V
L
K
D
P
V
G
R
E
Q
F
L
Zebra Danio
Brachydanio rerio
NP_001002541
459
53605
Q324
E
A
S
K
E
P
G
Q
T
R
V
R
R
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523380
647
70137
D518
S
L
R
E
L
L
N
D
A
I
G
R
E
Q
F
Honey Bee
Apis mellifera
XP_393403
510
59946
P385
L
Q
E
L
L
Q
D
P
I
G
R
E
Q
F
I
Nematode Worm
Caenorhab. elegans
P49809
555
63260
I394
Q
S
Q
P
N
P
W
I
N
D
T
V
D
F
W
Sea Urchin
Strong. purpuratus
XP_782272
467
54702
L332
G
F
S
F
D
D
L
L
K
D
S
L
G
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
98.8
51
N.A.
91.3
95.1
N.A.
76.8
87.7
70.3
83
N.A.
41.2
53.5
34.5
56.1
Protein Similarity:
100
96.7
98.8
61.9
N.A.
93.7
96.1
N.A.
79.2
91.9
81.8
87.8
N.A.
53.7
71.9
51.1
71.9
P-Site Identity:
100
100
100
93.3
N.A.
6.6
13.3
N.A.
100
100
6.6
6.6
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
20
33.3
N.A.
100
100
20
33.3
N.A.
20
20
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
15
8
22
8
0
15
0
0
8
0
8
% D
% Glu:
15
0
22
50
8
43
0
0
0
50
0
22
8
0
0
% E
% Phe:
0
50
0
8
0
0
43
0
0
0
0
8
0
72
15
% F
% Gly:
8
0
0
0
0
0
8
8
0
22
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
8
% I
% Lys:
36
0
0
15
0
15
0
0
8
0
0
0
0
8
0
% K
% Leu:
15
8
50
8
29
8
8
8
0
0
0
50
8
0
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
8
0
8
0
43
0
0
0
0
% N
% Pro:
0
0
0
8
0
22
0
22
0
0
0
0
0
0
0
% P
% Gln:
8
8
8
0
0
8
0
8
0
0
8
0
22
8
0
% Q
% Arg:
8
0
8
0
0
0
0
0
8
8
22
15
50
8
0
% R
% Ser:
8
8
15
0
43
0
0
43
43
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
15
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
50
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _